Publications |
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Quality control of un-imported mitochondrial proteins at a glance. Journal of Cell Science (2025)
Megan Balzarini, John Kim, and Hilla Weidberg. Link Protocol for assessing the clogging of the mitochondrial translocase of the outer membrane by precursor proteins in human cells. STAR protocols (2025) John Kim, and Hilla Weidberg. Link ATAD1 prevents clogging of TOM and damage caused by un-imported mitochondrial proteins. Cell Reports (2024) John Kim, Madeleine Goldstein, Lauren Zecchel, Ryan Ghorayeb, Christopher A Maxwell, Hilla Weidberg. Link * Research Highlighted in: Bohnert, M., Gatsogiannis, C., Herrmann, JM. Trends in Cell Biology. 2024 MitoStores: a place for precursors to ride out the storm. EMBO Journal (2023) Balzarini M., Yuan Z., Weidberg H. UPRmt scales mitochondrial network expansion with protein synthesis via mitochondrial import in Caenorhabditis elegans. Nature Communication (2021) Shpilka, T., Du, Y.G., Yang Q., Melber A., Naresh N.U., Lavelle J., Liu P., Weidberg H., Li R., Yu J., Zhu L.J., Strittmatter L., Haynes C.M. Link MitoCPR- A surveillance pathway that protects mitochondria in response to protein import stress. Science (2018) Weidberg H#, Amon A# (corresponding author) Link * Research Highlighted in: Desai R, Campanella M. Mol Cell. 2018 Jul 5;71(1):8-9. Pires J, Haynes CM. Curr Biol. 2018 Jun 4;28(11) NEK3-mediated SNAP29 phosphorylation modulates its membrane association and SNARE fusion dependent processes. Biochem Biophys Res Commun (2018). Rapaport D, Fichtman B, Weidberg H, Sprecher E, Horowitz M. Link Nutrient control of yeast gametogenesis is mediated by TORC1, PKA and energy availability. PLoS Genetics (2016). Weidberg H, Moretto F, Spedale G, Amon A, J. van Werven F. Link EHD2 shuttles to the nucleus and represses transcription. Biochem J. (2012) Pekar O, Benjamin S, Weidberg H, Smaldone S, Ramirez F, Horowitz M. Link Atg8, an autophagic-related ubiquitin-like protein family. Genome Biol (2011) Shpilka T, Weidberg H, Pietrokovski S, Elazar Z. Link LC3 and GATE-16 N-termini mediate membrane fusion processes required for autophagosome biogenesis. Dev. Cell (2011) Weidberg H, Shpilka T, Shvets E, Abada Adi, Shimron F, Elazar Z. Link * Recommendation by Faculty of 1000. TBK1 mediates cross-talk between the innate immune response and autophagy. Sci Signal. (2011) Weidberg H, Elazar Z. Biogenesis and cargo selectivity of autophagosomes. Ann Rev Biochem (2011) Weidberg H, Shvets E, Elazar, Z. Link Dissecting the involvement of LC3B and GATE-16 in p62 recruitment into autophagosomes. Autophagy (2011) Shvets E, Abada A, Weidberg H, Elazar Z. Link EHD2 mediates trafficking from the plasma membrane by modulating Rac1 activity. Biochem J. (2011) Benjamin S, Weidberg H, Rapaport D, Pekar O, Nudelman M, Segal D, Hirschberg K, Katzav S, Ehrlich M, Horowitz M. Link Mammalian Atg8s: one is simply not enough. Autophagy (2010) Weidberg H, Shpilka T, Shvets E, Elazar Z. LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis. EMBO J (2010) Weidberg H, Shvets E, Shpilka T, Shimron F, Shinder V, Elazar Z. Link p53-dependent regulation of autophagy provides cancer cells with a survival advantage under prolonged starvation. PNAS (2010) Scherz-Shouval R, Weidberg H, Gonen C, Wilder S, Elazar Z, Oren M. Link Lipophagy: selective catabolism designed for lipids. Dev Cell (2009) Weidberg H, Shvets E, Elazar Z. |